Hepatic branch vagus nerve plays a critical role in the recovery of post-ischemic glucose intolerance and mediates a neuroprotective effect by hypothalamic orexin-A.

Orexin-A (a neuropeptide in the hypothalamus) plays an important role in many physiological functions, including the regulation of glucose metabolism.We have previously found that the development of post-ischemic glucose intolerance is one of the triggers of ischemic neuronal damage, which is suppressed by hypothalamic orexin-A.Other reports have s

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Neural Correlates of Suspiciousness and Interactions with Anxiety during Emotional and Neutral Word Processing

Suspiciousness is usually classified as a symptom of psychosis, but it also occurs in depression and anxiety disorders.Though how suspiciousness overlaps with depression is not obvious, suspiciousness does seem to overlap with anxious apprehension and anxious arousal (e.g., verbal iterative processes and vigilance about environmental threat).Howeve

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Preeclampsia impedes foetal kidney development by delivering placenta-derived exosomes to glomerular endothelial cells

Abstract Background Foetal renal dysplasia is still the main cause of adult renal disease.Placenta-derived exosomes are an important communication tool, and they may play an important role in placental (both foetal and maternal) Replacement Part function.We hypothesize that in women with preeclampsia, foetal renal dysplasia is impeded by delivering

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